It depends on the amount of your gift. Memorial Blood Centers will issue you a receipt for any amount you contribute. However, typically the IRS does not require a receipt for any gift of $249.99 or less. For a single gift of $250 or more, you are required to have a receipt to substantiate your claim.
If you make a quid pro quo contribution—that is, you receive goods or services in exchange for a portion of your gift—Memorial Blood Centers is required to issue a receipt specifying the amount of the contribution and the goods and/or services received. For example, if you attend a benefit dinner and your charitable contribution includes the cost of the dinner, then that cost must be subtracted from your charitable deduction.